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Researcher
- Diana E Hun
- Adam M Guss
- Kashif Nawaz
- Kyle Gluesenkamp
- Som Shrestha
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- Zhenglai Shen

Mechanism-Based Trait Inference in Plants Using Multiplex Networks, AI Agents, and Translation Tools
This system enables the modular design and optimization of complex plant traits by organizing genes and regulatory mechanisms into interpretable clades.

Mechanism-Based Biological Inference via Multiplex Networks, AI Agents and Cross-Species Translation
This invention provides a platform that uses AI agents and biological networks to uncover and interpret disease-relevant biological mechanisms.

Enzymes for synthesis of sequenced oligoamide triads and tetrads that can be polymerized into sequenced copolyamides.
Contact
To learn more about this technology, email partnerships@ornl.gov or call 865-574-1051.

We tested 48 diverse homologs of SfaB and identified several enzyme variants that were more active than SfaB at synthesizing the nylon-6,6 monomer.

We’ve developed a more cost-effective cable driven robot system for installing prefabricated panelized building envelopes. Traditional cable robots use eight cables, which require extra support structures, making setup complex and expensive.

We presented a novel apparatus and method for laser beam position detection and pointing stabilization using analog position-sensitive diodes (PSDs).

We have developed thermophilic bacterial strains that can break down PET and consume ethylene glycol and TPA. This will help enable modern, petroleum-derived plastics to be converted into value-added chemicals.

By engineering the Serine Integrase Assisted Genome Engineering (SAGE) genetic toolkit in an industrial strain of Aspergillus niger, we have established its proof of principle for applicability in Eukaryotes.

US coastal and island communities have vulnerable energy infrastructure and high energy costs, which are exacerbated by climate change.

The invention presented here addresses key challenges associated with counterfeit refrigerants by ensuring safety, maintaining system performance, supporting environmental compliance, and mitigating health and legal risks.