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- Adam M Guss
- Sheng Dai
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- Yasemin Kaygusuz
- Zoriana Demchuk

Mechanism-Based Trait Inference in Plants Using Multiplex Networks, AI Agents, and Translation Tools
This system enables the modular design and optimization of complex plant traits by organizing genes and regulatory mechanisms into interpretable clades.

Mechanism-Based Biological Inference via Multiplex Networks, AI Agents and Cross-Species Translation
This invention provides a platform that uses AI agents and biological networks to uncover and interpret disease-relevant biological mechanisms.

Enzymes for synthesis of sequenced oligoamide triads and tetrads that can be polymerized into sequenced copolyamides.
Contact
To learn more about this technology, email partnerships@ornl.gov or call 865-574-1051.

We tested 48 diverse homologs of SfaB and identified several enzyme variants that were more active than SfaB at synthesizing the nylon-6,6 monomer.

We have developed thermophilic bacterial strains that can break down PET and consume ethylene glycol and TPA. This will help enable modern, petroleum-derived plastics to be converted into value-added chemicals.

A novel strategy was developed to solve the limitations of the current sorbent systems in CO2 chemisorption in terms of energy consumption in CO2 release and improved CO2 uptake capacity.

By engineering the Serine Integrase Assisted Genome Engineering (SAGE) genetic toolkit in an industrial strain of Aspergillus niger, we have established its proof of principle for applicability in Eukaryotes.

This invention introduces a novel sintering approach to produce hard carbon with a finely tuned microstructure, derived from biomass and plastic waste.

Estimates based on the U.S. Department of Energy (DOE) test procedure for water heaters indicate that the equivalent of 350 billion kWh worth of hot water is discarded annually through drains, and a large portion of this energy is, in fact, recoverable.

We present a comprehensive muti-technique approach for systematic investigation of enzymes generated by wastewater Comamonas species with hitherto unknown functionality to wards the depolymerization of plastics into bioaccessible products for bacterial metabolism.