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This system enables the modular design and optimization of complex plant traits by organizing genes and regulatory mechanisms into interpretable clades.

This invention provides a platform that uses AI agents and biological networks to uncover and interpret disease-relevant biological mechanisms.

Enzymes for synthesis of sequenced oligoamide triads and tetrads that can be polymerized into sequenced copolyamides.

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To learn more about this technology, email partnerships@ornl.gov or call 865-574-1051.

We tested 48 diverse homologs of SfaB and identified several enzyme variants that were more active than SfaB at synthesizing the nylon-6,6 monomer.

By engineering the Serine Integrase Assisted Genome Engineering (SAGE) genetic toolkit in an industrial strain of Aspergillus niger, we have established its proof of principle for applicability in Eukaryotes.

The lack of real-time insights into how materials evolve during laser powder bed fusion has limited the adoption by inhibiting part qualification.  The developed approach provides key data needed to fabricate born qualified parts.

We present a comprehensive muti-technique approach for systematic investigation of enzymes generated by wastewater Comamonas species with hitherto unknown functionality to wards the depolymerization of plastics into bioaccessible products for bacterial metabolism.

A new nanostructured bainitic steel with accelerated kinetics for bainite formation at 200 C was designed using a coupled CALPHAD, machine learning, and data mining approach.

Digital twins (DTs) have emerged as essential tools for monitoring, predicting, and optimizing physical systems by using real-time data.

Simulation cloning is a technique in which dynamically cloned simulations’ state spaces differ from their parent simulation due to intervening events.