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Enzymes for synthesis of sequenced oligoamide triads and tetrads that can be polymerized into sequenced copolyamides.
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We tested 48 diverse homologs of SfaB and identified several enzyme variants that were more active than SfaB at synthesizing the nylon-6,6 monomer.
This technology identifies enzymatic routes to synthesize amide oligomers with defined sequence to improve polymerization of existing materials or enable polymerization of new materials. Polymers are generally composed of one (e.g. Nylon 6) or two (e.g.