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The invention teaches a method for separating uranium and the transuranic actinides neptunium, plutonium, and americium from nitric acid solutions by co-crystallization upon lowering the temperature from 60 C to 20 C or lower.

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By engineering the Serine Integrase Assisted Genome Engineering (SAGE) genetic toolkit in an industrial strain of Aspergillus niger, we have established its proof of principle for applicability in Eukaryotes.