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Biocompatible nanoparticles have been developed that can trap and retain therapeutic radionuclides and their byproducts at the cancer site. This is important to maximize the therapeutic effect of this treatment and minimize associated side effects.

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Ionic liquids comprising quaternary ammonium and phosphonium cations have been developed as eco-friendly lubricant additives. These additives are tailored for use in environmentally acceptable lubricants (EALs) like polyalkylene glycols, vegetable oils, and synthetic esters.

Neodymium magnet on white. Adobe Stock

High-performance cerium-based permanent magnet materials have been developed to reduce reliance on scarce rare-earth elements.

ORNL scientists identified four amino acids key to signaling pathways in the PAN protein domain. Mutating any of those disrupted the signal that tells cancer cells to multiply. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy

An ORNL team has developed a method for screening for an immunoregulatory protein, which includes assessing the sequence of a candidate protein to determine if it is an immunoregulatory protein when at least one plasminogen-apple-nematode (PAN) domain with a consensus sequence