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This system enables the modular design and optimization of complex plant traits by organizing genes and regulatory mechanisms into interpretable clades.

This invention provides a platform that uses AI agents and biological networks to uncover and interpret disease-relevant biological mechanisms.

Enzymes for synthesis of sequenced oligoamide triads and tetrads that can be polymerized into sequenced copolyamides.

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To learn more about this technology, email partnerships@ornl.gov or call 865-574-1051.

We tested 48 diverse homologs of SfaB and identified several enzyme variants that were more active than SfaB at synthesizing the nylon-6,6 monomer.

By engineering the Serine Integrase Assisted Genome Engineering (SAGE) genetic toolkit in an industrial strain of Aspergillus niger, we have established its proof of principle for applicability in Eukaryotes.

CO2 capture by mineral looping, either using calcium or magnesium precursors requires that the materials be calcined after CO2 is captured from the atmosphere. This separates the CO2 for later sequestration and returned the starting material to its original state.

This manufacturing method uses multifunctional materials distributed volumetrically to generate a stiffness-based architecture, where continuous surfaces can be created from flat, rapidly produced geometries.

The lack of real-time insights into how materials evolve during laser powder bed fusion has limited the adoption by inhibiting part qualification.  The developed approach provides key data needed to fabricate born qualified parts.

We present a comprehensive muti-technique approach for systematic investigation of enzymes generated by wastewater Comamonas species with hitherto unknown functionality to wards the depolymerization of plastics into bioaccessible products for bacterial metabolism.

Mineral looping is a promising method for direct air capture of CO2. However, reduction of sorbent reactivity after each loop is likely to be significant problems for mineral looping by MgO.