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We have developed thermophilic bacterial strains that can break down PET and consume ethylene glycol and TPA. This will help enable modern, petroleum-derived plastics to be converted into value-added chemicals.

By engineering the Serine Integrase Assisted Genome Engineering (SAGE) genetic toolkit in an industrial strain of Aspergillus niger, we have established its proof of principle for applicability in Eukaryotes.

We present a comprehensive muti-technique approach for systematic investigation of enzymes generated by wastewater Comamonas species with hitherto unknown functionality to wards the depolymerization of plastics into bioaccessible products for bacterial metabolism.

This technology can activate gene expression in a time- and dose-dependent manner in the thermophilic bacterium Clostridium thermocellum. This system will mediate inducible gene expression for strain engineering in C.

The technologies described provides for the upcycling of mixed plastics to muonic acid and 3-hydroxyacids.

This invention is for bacterial strains that can utilize lignocellulose sugars. This will improve the efficiency of bioproduct formation in these strains and reduce the greenhouse-gas emission of an industrial bi

ORNL has developed bacterial strains that can utilize a common plastic co-monomer as a feedstock. This will help enable modern, petroleum-derived plastics to be converted into value-added chemicals.

We have developed bacterial strains that can convert sustainable feedstocks and waste feedstocks into chemical precursors for next generation plastics.

ORNL has identified a panel of novel nylon hydrolases with varied substrate and product selectivity.

Genetic modification of microbes that are thermophiles—ones that grow at elevated temperatures—is extremely challenging. Tools developed for E. coli, a typical host for protein production, typically do not function at elevated temperatures.