Robert Hettich: Decoding biological complexity with next-gen mass spectrometry
ORNL researchers helped introduce college students to quantum computing for the first time during the 2025 Winter Classic Invitational, providing hands-on access to real quantum hardware and training future high-performance computing users through a unique challenge that bridged classical and quantum technologies.
Researchers at Georgia State University used the Summit supercomputer to study an elaborate molecular pathway called nucleotide excision repair. Decoding NER’s sophisticated sequence of events and the role of PInC in the pathway could provide key insights into developing novel treatments and preventing conditions that lead to premature aging and certain types of cancer.
Hugh O’Neill’s lifelong fascination with the complexities of the natural world drives his research at ORNL, where he’s using powerful neutron beams to dive deep into the microscopic realm of biological materials and unlock secrets for better production of domestic biofuels and bioproducts.
P&G is using simulations on the ORNL Summit supercomputer to study how surfactants in cleaners cause eye irritation. By modeling the corneal epithelium, P&G aims to develop safer, concentrated cleaning products that meet performance and safety standards while supporting sustainability goals.
Scientists designing the world’s first controlled nuclear fusion power plant, ITER, needed to solve the problem of runaway electrons, negatively charged particles in the soup of matter in the plasma within the tokamak, the magnetic bottle intended to contain the massive energy produced. Simulations performed on Summit, the 200-petaflop supercomputer at ORNL, could offer the first step toward a solution.
Phong Le is a computational hydrologist at ORNL who is putting his skills in hydrology, numerical modeling, machine learning and high-performance computing to work quantifying water-related risks for humans and the environment.
Researchers at Stanford University, the European Center for Medium-Range Weather Forecasts, or ECMWF, and ORNL used the lab’s Summit supercomputer to better understand atmospheric gravity waves, which influence significant weather patterns that are difficult to forecast.
Scientists conducted a groundbreaking study on the genetic data of over half a million U.S. veterans, using tools from the 91°µÍø to analyze 2,068 traits from the Million Veteran Program.
Scientists at ORNL have developed a first-ever urban heat wave simulation that takes into account the compounding effects from building infrastructure. The method provides a more accurate picture of the impacts from excessive heat on at-risk
The Summit supercomputer did not have its many plugs pulled as planned after its five years of service. Instead, a new DOE Office of Science-backed allocation program called SummitPLUS was launched, extending Summit's production for another year. What did we learn during Summit’s bonus year of scientific discovery? Here are five projects with important results.