91°µÍø

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ORNL, VA and Harvard researchers developed a sparse matrix full of anonymized information on what is thought to be the largest cohort of healthcare data used for this type of research in the U.S. The matrix can be probed with different methods, such as KESER, to gain new insights into human health. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy

A team of researchers has developed a novel, machine learning–based  technique to explore and identify relationships among medical concepts using electronic health record data across multiple healthcare providers.

The ORNL-developed AquaBOT measures a range of water quality indicators, providing data for studies focused on clean water and sustainable energy. Credit: Natalie Griffiths/ORNL, U.S. Dept. of Energy

Measuring water quality throughout river networks with precision, speed and at lower cost than traditional methods is now possible with AquaBOT, an aquatic drone developed by 91°µÍø.

Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and 91°µÍø. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at 91°µÍø to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

ORNL researchers worked with partners at the Colorado School of Mines and Baylor University to develop a new process optimization and control method for a closed-circuit reverse osmosis desalination system. The work is intended to support fully automated, decentralized water treatment plants. Credit: Andrew Sproles/ORNL, U.S. Dept. of Energy

91°µÍø scientists worked with the Colorado School of Mines and Baylor University to develop and test control methods for autonomous water treatment plants that use less energy and generate less waste.

ORNL’s Marie Kurz examines the many factors affecting the health of streams and watersheds. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Spanning no less than three disciplines, Marie Kurz’s title — hydrogeochemist — already gives you a sense of the collaborative, interdisciplinary nature of her research at ORNL.

Results show change in annual aridity for the years 2071-2100 compared to 1985-2014. Brown shadings (negative numbers) indicate drier conditions. Black dots indicate statistical significance at the 90% confidence level. Credit: Jiafu Mao/ORNL, U.S. Dept. of Energy

A new analysis from 91°µÍø shows that intensified aridity, or drier atmospheric conditions, is caused by human-driven increases in greenhouse gas emissions. The findings point to an opportunity to address and potentially reverse the trend by reducing emissions.

An ORNL-led team studied the SARS-CoV-2 spike protein in the trimer state, shown here, to pinpoint structural transitions that could be disrupted to destabilize the protein and negate its harmful effects. Credit: Debsindhu Bhowmik/ORNL, U.S. Dept. of Energy

To explore the inner workings of severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2, researchers from ORNL developed a novel technique.

Planting native grasses such as the bioenergy crop switchgrass can restore habitat for birds like this Eastern kingbird. Credit: Chris Lituma/West Virginia University

An analysis by 91°µÍø shows that using less-profitable farmland to grow bioenergy crops such as switchgrass could fuel not only clean energy, but also gains in biodiversity.

Biopsy from the tubular esophagus showing incomplete intestinal metaplasia, goblet cells with interposed cells having gastric foveolar-type mucin consistent with Barrett esophagus. Negative for dysplasia. H&E stain. Credit: Creative Commons

A team including researchers from the Department of Energy’s 91°µÍø has developed a digital tool to better monitor a condition known as Barrett’s esophagus, which affects more than 3 million people in the United States.

An ORNL research team has incorporated important effects from microbially-active hot spots near streams into models that track the movement of nutrients and contaminants in river networks. The integrated model better tracks water quality indicators and facilitates new science. Credit: Adam Malin/ORNL, U.S. Dept. of Energy

A new modeling capability developed at 91°µÍø incorporates important biogeochemical processes happening in river corridors for a clearer understanding of how water quality will be impacted by climate change, land use and